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Results for "

MS 154

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-141640
    MS154

    		PROTACs EGFR Cancer
    MS154 is a first-in-class E3 ligase cereblon-recruiting EGFR degrader with Kds of 1.8 nM and 3.8 nM for EGFR WT and EGFR L858R mutants. MS154 potently inhibits cell proliferation in lung cancer cells .
    <em>MS154</em>
  • HY-157579
    MS154N

    		EGFR Cancer
    MS154N (compound 28) is the negative control of MS39 (HY-157581). MS39 is a potent and selective EGFR degrader. MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells .
    <em>MS154</em>N

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